BDBM50263263 CHEMBL4073443

SMILES Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCCCC1

InChI Key InChIKey=HKTBYUWLRDZAJK-UHFFFAOYSA-N

Data  2 KI  13 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263263   

TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
A*Star

Curated by ChEMBL
LigandPNGBDBM50263263(CHEMBL4073443)
Affinity DataIC50:  6nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin) in HCT-116 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
A*Star

Curated by ChEMBL
LigandPNGBDBM50263263(CHEMBL4073443)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of Ser 209 phosphorylation of eIF4E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed